Rapid tranquillisation in psychiatric emergency settings in India: pragmatic randomised controlled trial of intramuscular olanzapine versus intramuscular haloperidol plus promethazine
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منابع مشابه
Rapid tranquillisation in psychiatric emergency settings in India: pragmatic randomised controlled trial of intramuscular olanzapine versus intramuscular haloperidol plus promethazine.
OBJECTIVE To compare the effect of intramuscular olanzapine with intramuscular haloperidol plus promethazine on rapid tranquillisation of agitated or violent people with mental illness. DESIGN Pragmatic, allocation concealed, randomised controlled trial. SETTING Emergency services of a general hospital psychiatry department in Vellore, south India. PARTICIPANTS 300 adults with agitated or...
متن کاملRapid tranquillisation in psychiatric emergency settings in Brazil: pragmatic randomised controlled trial of intramuscular haloperidol versus intramuscular haloperidol plus promethazine.
OBJECTIVE To determine whether haloperidol alone results in swifter and safer tranquillisation and sedation than haloperidol plus promethazine. DESIGN Pragmatic randomised open trial (January-July 2004). SETTING Psychiatric emergency room, Rio de Janeiro, Brazil. PARTICIPANTS 316 patients who needed urgent intramuscular sedation because of agitation, dangerous behaviour, or both. INTERV...
متن کاملRapid tranquillisation of violent or agitated patients in a psychiatric emergency setting. Pragmatic randomised trial of intramuscular lorazepam v. haloperidol plus promethazine.
BACKGROUND The pharmacological management of violence in people with psychiatric disorders is under-researched. AIMS To compare interventions commonly used for controlling agitation or violence in people with serious psychiatric disorders. METHOD We randomised 200 people to receive intramuscular lorazepam (4 mg) or intramuscular haloperidol (10 mg) plus promethazine (25-50 mg mix). RESULT...
متن کاملRapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.
OBJECTIVE To compare two widely used drug treatments for people with aggression or agitation due to mental illness. DESIGN Pragmatic, randomised clinical trial. SETTING Three psychiatric emergency rooms in Rio de Janeiro, Brazil. SUBJECTS 301 aggressive or agitated people. INTERVENTIONS Open treatment with intramuscular midazolam or intramuscular haloperidol plus promethazine. MAIN OU...
متن کاملefficacy of intramuscular haloperidol versus haloperidol plus promethazine in controlling aggressive behavior of psychiatric patients admitted to emergency rooms
abstract introduction: the aim of this study was to compare the therapeutic and adverse effects of haloperidol to the combination of haloperidol and promethazine (antipsychotic + antihistamine) for controlling patients with aggressive or violent behavior referred to psychiatric emergency rooms. methods: using a double-blind randomized controlled trial, 100 psychiatric patients admitted to emerg...
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ژورنال
عنوان ژورنال: BMJ
سال: 2007
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.39341.608519.be